chronoRCT
We find drugs with circadian potential
Discover hidden circadian potential in existing drugs with chronoRCT™, Arcascope’s precision platform for drug timing.
Why timing matters in medicine
Most drugs are tested and prescribed without considering the body’s internal clock. Yet circadian rhythms play a critical role in how drugs are absorbed, distributed, and metabolized. A medicine that’s safe and effective in the morning may cause side effects or lose efficacy if taken at night. Despite this, the vast majority of clinical trials overlook timing altogether—leading to promising therapies being abandoned, underutilized, or mischaracterized as ineffective. By ignoring when a drug is given, we risk losing treatments that could have worked if only time had been factored in.
Meet chronoRCT™.
chronoRCT™ is Arcascope’s proprietary platform for uncovering the hidden circadian potential in drugs.
- Generative PKPD models for timing potential from first principles, sculpted by data.
- Integrates tens of millions of wearable datapoints and 14,000+ gold-standard circadian biospecimen samples.
- Finds potential in failed or shelved assets through the dimension of time.
Of drugs hit targets with circadian variation
Of drugs are metabolized by CYP3A4, which is strongly circadian
The human genome is rhythmic
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